“Joint study showing the cross-sectional validity and utility of DANA as sensitive to cognitive impairment independently for concussion, PTSD, insomnia and depression. Objectives: Determine whether concussions uniquely impact emotional and cognitive functioning, independent of depression, PTSD, deployment history, or combat exposure, all of which can also negatively affect cognitive function. Methods: 646 active duty 2nd Marine Expeditionary Force members (avg. age of 22 years old) were administered a DANA test battery consisting of 8 neurocognitive tests and 5 self-reported psychological tests. Concussion history and deployment history were also collected. Neurocognitive test scores were analyzed with the inclusion of the surveys for combat exposure, depression, PTSD and deployment history as covariates to determine the relative factors influencing neurocognitive functioning. Results: The results revealed that the presence of three or more lifetime concussions was associated with a decrease in cognitive efficiency, independent of PTSD and depressive symptoms or likely diagnosis. Further, the presence of previous concussion, independent of previous deployment or combat exposure, was associated with worse levels of PTSD, depression, and insomnia. Sensitivity of DANA: Validity and utility of DANA was shown to be sensitive to changes in cognitive function from a variety of factors, including concussion, PTSD, insomnia and depression. The DANA tests on attention and simple discrimination were more sensitive to the effects of concussions than the more complex spatial processing or memory tests. “